Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.70 |
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849612 | 0.95 | MAPT (0.76) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21588758 | 0.89 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13167587 | 0.86 | RAB9A (0.75) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28600551 | 0.85 | MAPT (0.80) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6848441 | 0.85 | NPC1 (0.76) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4629429 | 0.84 | RAB9A (0.55) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12067341 | 0.80 | SIRT1 (0.71) | ALDH1A1MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL12316859 | 0.78 | RAB9A (0.78) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28662121 | 0.77 | SIRT1 (0.68) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2349003 | 0.76 | EPHX1 (0.73) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |