Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 12/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451571 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TTRHTTTSHR | |
| SCHEMBL5438292 | 0.82 | PLA2G4A (0.34) | PLA2G4ALTB4RALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14612638 | 0.78 | ACE2 (0.42) | ALDH1A1TTRTSHRMRGPRX4 | |
| SCHEMBL5448595 | 0.78 | TAS2R14 (0.43) | SMN1; SMN2CA1CA2CYP2C9 | |
| SCHEMBL5446944 | 0.76 | APOBEC3A (0.41) | ALDH1A1MAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL2424457 | 0.70 | CA12 (0.65) | PLA2G4ACA12CA1CA2CA4 | |
| SCHEMBL6859656 | 0.69 | CA12 (0.67) | PLA2G4ALTB4RCA12CA1CA2 | |
| SCHEMBL2592749 | 0.69 | CA12 (0.67) | PLA2G4AALDH1A1CA12CA1CA2 | |
| SCHEMBL9516446 | 0.66 | CA12 (0.62) | PLA2G4ACA12CA1CA2CA4 | |
| SCHEMBL2784039 | 0.66 | CA12 (0.62) | PLA2G4ACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |