Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445964 | 0.83 | PLA2G4A (0.45) | ALDH1A1TTRHTTTSHR | |
| SCHEMBL14612638 | 0.81 | ACE2 (0.42) | ALDH1A1TTRTSHR | |
| SCHEMBL5448132 | 0.81 | PDE10A (0.31) | — | |
| SCHEMBL5446944 | 0.72 | APOBEC3A (0.41) | ALDH1A1RAB9ATAS2R14TSHR | |
| SCHEMBL5448595 | 0.71 | TAS2R14 (0.43) | RAB9ATAS2R14AKR1C3AKR1C2 | |
| SCHEMBL27688707 | 0.70 | CASP6 (0.46) | RXRAEPHX2NR1H4CASP6TP53 | |
| SCHEMBL27879453 | 0.68 | RXRA (0.44) | ALDH1A1RXRAEPHX2NR1H4CASP6 | |
| SCHEMBL7513592 | 0.68 | EPHX2 (0.51) | ALDH1A1RXRAEPHX2NR1H4AGTR1 | |
| SCHEMBL14612641 | 0.67 | ACHE (0.45) | ALDH1A1RXRAEPHX2NR1H4TAS2R14 | |
| SCHEMBL17187158 | 0.66 | HPGD (0.41) | ALDH1A1LMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |