Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333342 | 0.82 | HTR3E (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4993304 | 0.78 | TRPA1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL342606 | 0.78 | TRPA1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4505209 | 0.77 | SLC22A2 (0.51) | SLC22A2NOS1NOS3LMNA | |
| Azobenzene SCHEMBL28504207 | 0.76 | ALDH1A1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4829863 | 0.76 | TRPA1 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL230956 | 0.75 | PLG (0.54) | NOS1NOS3CYP2C19TDP1MAPT | |
| SCHEMBL3962045 | 0.75 | SLC22A2 (0.54) | SLC22A2SLC22A1SLC22A3PLAUNOS1 | |
| SCHEMBL3081132 | 0.75 | F2 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL163160 | 0.75 | HTR3E (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7208 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024095026-A1 | IN VIVO TARGETING OF THERAPEUTIC MOLECULES TO THE RETINA VIA THE OPTICAL SYSTEM OF THE EYE | SEMMELWEIS EGYETEM (HU) | 2024-05-10 | — | — | WO | claimed |
| CN-109641940-B | Protoporphyrinogen oxidase variants and methods and compositions for conferring and/or enhancing herbicide tolerance using the same | 福阿母韩农株式会社 | 2022-11-18 | — | — | CN | claimed |
| CN-113248472-A | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2021-08-13 | — | — | CN | claimed |
| US-9935269-B2 | Electroluminescence element | Konica Minolta, Inc. (JP) | 2018-04-03 | — | — | US | claimed |
| US-9834022-B2 | Thermal recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2017-12-05 | — | — | US | claimed |
| US-9745474-B2 | Acid dyes, process for the production thereof and their use | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2017-08-29 | — | — | US | claimed |
| EP-2861670-B1 | METAL FREE REACTIVE DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2017-08-16 | — | — | EP | claimed |
| US-9725597-B2 | Acid dyes, process for the production thereof and their use | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2017-08-08 | — | — | US | claimed |
| EP-3063231-B1 | ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2017-05-17 | — | — | EP | claimed |
| EP-3063232-B1 | ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2017-05-17 | — | — | EP | claimed |
| EP-0010358-A1 | Beta-lactam compounds, processes for their preparation, compositions containing them, intermediates of use in their preparation and methods for the production thereof | GLAXO GROUP LIMITED (GB) | 1980-04-30 | — | — | EP | claimed |
| US-4147865-A | Benz-(C,D)-indolyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | claimed |
| US-4097594-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1978-06-27 | — | — | US | claimed |
| US-4063014-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1977-12-13 | — | — | US | claimed |
| US-4059448-A | SILVER HALIDE, POLY(2-DIETHYLAMINOETHYL METHACRYLATE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |
| US-4040840-A | MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | claimed |
| US-4026709-A | Color photographic recording material | CIBA-GEIGY AG (CH) | 1977-05-31 | — | — | US | claimed |
| US-4021428-A | 4-Piperidino-5-oxo-2-pyrazolines | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | claimed |
| US-3984432-A | PHOSPHONIC ACID AND PHOSPHORIC ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1976-10-05 | — | — | US | claimed |
| US-3956339-A | 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |