SCHEMBL4829863

SCHEMBL4829863

[O]C(=O)[N]c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HTR3E A5X5Y0 1/20 0.40
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
HTR3B O95264 1/20 0.40
PLAU P00749 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ALOX15 P16050 1/20 0.39
NPC1 O15118 2/20 0.39
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4993304 0.80 TRPA1 (0.46) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1
SCHEMBL342606 0.80 TRPA1 (0.46) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1
Azobenzene SCHEMBL9435350 0.77 ALDH1A1 (0.75) TRPA1ALDH1A1TSHRNPC1MEN1
Azobenzene SCHEMBL475771 0.77 ALDH1A1 (0.75) TRPA1ALDH1A1TSHRNPC1MEN1
SCHEMBL3743447 0.76 TRPA1 (0.43) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1
SCHEMBL834716 0.76 NOS3 (0.48) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1
SCHEMBL54470 0.76 HTR3E (0.50) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1
Nitrosobenzene SCHEMBL28787012 0.74 ALDH1A1 (0.52) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1
SCHEMBL2329631 0.74 CES1 (0.48) TRPA1ALDH1A1CES2CES1TSHR
SCHEMBL9333342 0.74 HTR3E (0.48) TRPA1ALDH1A1HTR3ESLC22A2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 US disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 US disclosed
EP-0790980-A1 2-CYANOACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 1997-08-27 EP disclosed
WO-1996015102-A2 2-CYANOACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 1996-05-23 WO disclosed