Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467840 | 0.80 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL5459614 | 0.77 | MCHR1 (0.42) | CYP3A4KDM4EMEN1TP53CYP1A2 | |
| SCHEMBL23545538 | 0.72 | KDM1A (0.56) | KDM1AMAOAMAOBCYP3A4KDM4E | |
| SCHEMBL30471890 | 0.72 | KDM1A (0.56) | KDM1AMAOAMAOBCYP3A4KDM4E | |
| SCHEMBL5449944 | 0.72 | MCHR1 (0.53) | CYP3A4KDM4EMEN1TP53CYP1A2 | |
| SCHEMBL19650812 | 0.68 | KDM1A (0.59) | KDM1AMAOAMAOBCYP3A4KDM4E | |
| SCHEMBL3946424 | 0.67 | CYP1A2 (0.42) | CYP3A4KDM4EMEN1TP53CYP1A2 | |
| SCHEMBL3938281 | 0.65 | MAPK14 (0.43) | CYP3A4KDM4EMEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL6626936 | 0.64 | ADRA2A (0.52) | CYP3A4KDM4EMEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL6614692 | 0.62 | MCHR1 (0.51) | CYP3A4KDM4EMEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185119-A1 | Therapeutic agents II | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | claimed |
| US-20070185119-A1 | Therapeutic agents II | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185119-A1 | Therapeutic agents II | HTT, ACHE, GPR119 | KDM1A 3678/4885MAOA 868/4885MAOB 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.