Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947195 | 0.83 | DCPS (0.53) | MCHR1ADRA2ADCPSEPHX2KDM4E | |
| Hydrochloric Acid SCHEMBL6614692 | 0.83 | MCHR1 (0.51) | MCHR1ADRA2ADCPSEPHX2PRKCQ | |
| Hydrochloric Acid SCHEMBL6626936 | 0.81 | ADRA2A (0.52) | MCHR1ADRA2ADCPSEPHX2NPY5R | |
| SCHEMBL5449944 | 0.80 | MCHR1 (0.53) | MCHR1KDM4EMEN1TP53CYP1A2 | |
| SCHEMBL5447272 | 0.77 | KDM1A (0.38) | MCHR1KDM4EMEN1TP53CYP1A2 | |
| SCHEMBL5467840 | 0.76 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL3947662 | 0.73 | MCHR1 (0.52) | MCHR1ADRA2ADCPSNPY5R | |
| Hydrochloric Acid SCHEMBL6604157 | 0.69 | ADRA2A (0.54) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13793982 | 0.68 | ADRA2A (0.61) | MCHR1ADRA2AEPHX2NPY5RCYP1A2 | |
| Hydrochloric Acid SCHEMBL3940142 | 0.67 | ADRA2A (0.60) | MCHR1ADRA2AEPHX2NPY5RCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185119-A1 | Therapeutic agents II | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | claimed |
| US-20070185119-A1 | Therapeutic agents II | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185119-A1 | Therapeutic agents II | HTT, ACHE, GPR119 | MCHR1 968/4885ADRA2A 702/4885DCPS 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.