SCHEMBL5448016

SCHEMBL5448016

CN(C)C(=S)Nc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TAS2R38 P59533 3/20 0.58
HSD17B10 Q99714 2/20 0.56
CYP3A4 P08684 1/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MASP2 O00187 1/20 0.55
GAA P10253 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
NOX1 Q9Y5S8 1/20 0.52
TP53 P04637 1/20 0.52
TYR P14679 1/20 0.52
TSHR P16473 1/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23618280 1.00 ALDH1A1 (0.61) ALDH1A1TAS2R38HSD17B10CYP3A4MEN1
SCHEMBL10670402 0.83 MEN1 (0.67) ALDH1A1TAS2R38HSD17B10CYP3A4MEN1
SCHEMBL10394940 0.81 LMNA (0.66) ALDH1A1TAS2R38HSD17B10CYP3A4MEN1
SCHEMBL10566568 0.81 SMN1; SMN2 (0.55) ALDH1A1MEN1KMT2AMASP2GAA
SCHEMBL5450380 0.80 ALDH1A1 (0.58) ALDH1A1CYP3A4MEN1KMT2AGAA
SCHEMBL622887 0.79 MAPT (0.54) ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A
SCHEMBL28349654 0.79 TAS2R38 (0.50) ALDH1A1TAS2R38HSD17B10CYP3A4MEN1
SCHEMBL5454000 0.78 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AGAARAB9A
SCHEMBL11548182 0.78 MAPT (0.52) ALDH1A1TAS2R38CYP3A4MEN1KMT2A
SCHEMBL11775744 0.78 KMT2A (0.61) ALDH1A1CYP3A4MEN1KMT2AMASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120041182-A Particle size-controllable epoxy resin fracturing propping agent and preparation method thereof 江苏扬农化工集团有限公司 2025-05-27 CN claimed
CN-120041182-A Particle size-controllable epoxy resin fracturing propping agent and preparation method thereof 江苏扬农化工集团有限公司 2025-05-27 CN disclosed
US-20230295236-A1 COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS PHARMA MAR, S.A. (ES) 2023-09-21 US disclosed
JP-2022113139-A SKIN WHITENING COMPOSITION CONTAINING DIMETHYLPHENYLTHIOUREA コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー 2022-08-03 JP disclosed
US-20160317511-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA COR THERAPEUTICS, INC. 2016-11-03 US disclosed
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
US-8691847-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2014-04-08 US disclosed
US-20130172310-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA MILLENNIUM PHARMACEUTICALS, INC. 2013-07-04 US disclosed
US-20110108780-A1 Cellulose Acetate Film SK ENERGY CO., LTD. (KR) 2011-05-12 US disclosed
US-20110108780-A1 Cellulose Acetate Film SK ENERGY CO., LTD. (KR) 2011-05-12 US disclosed
US-4307238-A Substituted 2-imino-1,3-dithio and 1,3-oxathio heterocyclic compounds as herbicidal antidotes MONSANTO COMPANY (US) 1981-12-22 US disclosed
US-4252963-A CYCLIZATION OF PHENYLTHIOUREAS WITH THIONYL CHLORIDE HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed
US-4231783-A APPLYING AS A MIXTURE WITH A THIOCARBAMATE OR ACETANILIDE TO RICE, SORGHUM OR WHEAT MONSANTO COMPANY (US) 1980-11-04 US disclosed
EP-0011473-A1 Substituted 2-imino-1,3-dithio and 1,3-oxathio heterocyclic compounds as herbicidal antidotes MONSANTO COMPANY (US) 1980-05-28 EP disclosed
US-4203897-A Penam derivatives FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-05-20 US disclosed
US-4176017-A ACRYLAMIDE POLYMER, BORATE OR THIOUREA DERIVATIVE OXY METAL INDUSTRIES CORPORATION (US) 1979-11-27 US disclosed
US-4084049-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-04-11 US disclosed
US-3996275-A HERBICIDES MONSANTO COMPANY (US) 1976-12-07 US disclosed
US-3956384-A HERBICIDE MONSANTO COMPANY (US) 1976-05-11 US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160317511-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA TFPI, F12, TFPI2 ALDH1A1 2339/4885TAS2R38 3137/4885HSD17B10 3314/4885
US-20230295236-A1 COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS TLR4, TLR3, TLR2 ALDH1A1 784/4885TAS2R38 1962/4885HSD17B10 1738/4885
US-20130172310-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA TFPI, F12, TFPI2 ALDH1A1 2339/4885TAS2R38 3137/4885HSD17B10 3314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.