Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MASP2 | O00187 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448016 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TAS2R38HSD17B10CYP3A4MEN1 | |
| SCHEMBL10670402 | 0.83 | MEN1 (0.67) | ALDH1A1TAS2R38HSD17B10CYP3A4MEN1 | |
| SCHEMBL10394940 | 0.81 | LMNA (0.66) | ALDH1A1TAS2R38HSD17B10CYP3A4MEN1 | |
| SCHEMBL10566568 | 0.81 | SMN1; SMN2 (0.55) | ALDH1A1MEN1KMT2AMASP2GAA | |
| SCHEMBL5450380 | 0.80 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MEN1KMT2AGAA | |
| SCHEMBL622887 | 0.79 | MAPT (0.54) | ALDH1A1TAS2R38HSD17B10CYP3A4KMT2A | |
| SCHEMBL28349654 | 0.79 | TAS2R38 (0.50) | ALDH1A1TAS2R38HSD17B10CYP3A4MEN1 | |
| SCHEMBL5454000 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AGAARAB9A | |
| SCHEMBL11548182 | 0.78 | MAPT (0.52) | ALDH1A1TAS2R38CYP3A4MEN1KMT2A | |
| SCHEMBL11775744 | 0.78 | KMT2A (0.61) | ALDH1A1CYP3A4MEN1KMT2AMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210205467-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205467-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | IGF2R, CFH, M6PR | ALDH1A1 174/4885TAS2R38 2635/4885HSD17B10 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.