Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699709 | 0.92 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL4700388 | 0.87 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL4699632 | 0.87 | P2RX7 (0.53) | P2RX7MAPK8 | |
| SCHEMBL4696025 | 0.83 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL4750584 | 0.82 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL4755588 | 0.81 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL5450184 | 0.81 | ALDH1A1 (0.47) | MAPK8 | |
| SCHEMBL3288038 | 0.76 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL4698607 | 0.76 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL5441843 | 0.71 | TSHR (0.48) | MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | ABBOTT LABORATORIES | 2007-11-08 | — | — | US | claimed |
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | ABBOTT LABORATORIES | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | P2RX7, P2RX1, P2RX3 | P2RX7 1/4885MAPK8 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.