Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698588 | 0.93 | GAA (0.47) | ALDH1A1GAAPOLBMAPK8KMT2A | |
| SCHEMBL5441843 | 0.88 | TSHR (0.48) | ALDH1A1GAAPOLBMAPK8KMT2A | |
| SCHEMBL5448323 | 0.87 | ENPP2 (0.49) | ALDH1A1GAAPOLBMAPK8KMT2A | |
| SCHEMBL5448123 | 0.85 | ENPP2 (0.42) | ALDH1A1GAAPOLBKMT2AENPP2 | |
| SCHEMBL5476310 | 0.83 | TSHR (0.42) | ALDH1A1GAAPOLBKMT2AENPP2 | |
| SCHEMBL5448293 | 0.81 | P2RX7 (0.54) | MAPK8 | |
| SCHEMBL4699709 | 0.74 | P2RX7 (0.51) | — | |
| SCHEMBL4700388 | 0.71 | P2RX7 (0.50) | — | |
| SCHEMBL5446699 | 0.71 | MEN1 (0.53) | ALDH1A1POLBKMT2AENPP2 | |
| SCHEMBL5449752 | 0.69 | MEN1 (0.61) | ALDH1A1POLBKMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | ABBOTT LABORATORIES | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | P2RX7, P2RX1, P2RX3 | ALDH1A1 2161/4885GAA 3104/4885POLB 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.