Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544908 | 1.00 | ERN1 (0.60) | ERN1GABRA3GABRA2GABRB2CA2 | |
| SCHEMBL9358828 | 0.87 | TRIM24 (0.60) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL7138832 | 0.84 | JUN (0.58) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9358863 | 0.81 | ERN1 (0.53) | ERN1GABRA3GABRA2GABRB2CA2 | |
| SCHEMBL1416591 | 0.80 | EGFR (0.58) | CA2CA1ALDH1A1HPGDMAPT | |
| SCHEMBL706050 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TRIM24TYRTRIM33CYP3A4 | |
| SCHEMBL706049 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TRIM24TYRTRIM33CYP3A4 | |
| SCHEMBL8746634 | 0.78 | AKR1C3 (0.53) | CA2CA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL3423297 | 0.78 | AKR1C3 (0.53) | CA2CA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9359090 | 0.76 | USP2 (0.45) | ERN1CA2CA1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110589-B2 | Ectoparasiticide composition and a method for exterminating extoparasites | KYOYU AGRI CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20090312378-A1 | ECTOPARASITICIDE COMPOSITION AND A METHOD FOR EXTERMINATING ECTOPARASITES | YASHIMA SANGYO CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-0489836-B1 | LIGHT ACTIVATED ACYL-ENZYMES | UNIV DUKE (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5218137-A | Chemical light amplifiers | DUKE UNIVERSITY (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0489836-A4 | LIGHT ACTIVATED ACYL-ENZYMES | — | 1993-05-26 | — | — | EP | disclosed |
| EP-0489836-A1 | LIGHT ACTIVATED ACYL-ENZYMES. | UNIV DUKE (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5114851-A | Serine- or cysteine-containing protease modified by nucleophilic cinnamic acid; photoisomerization; biological switches; medical diagnosis | DUKE UNIVERSITY (US) | 1992-05-19 | — | — | US | disclosed |
| WO-1991003549-A1 | LIGHT ACTIVATED ACYL-ENZYMES | DUKE UNIVERSITY (US) | 1991-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312378-A1 | ECTOPARASITICIDE COMPOSITION AND A METHOD FOR EXTERMINATING ECTOPARASITES | EPX, TYR, PPOX | ERN1 2741/4885GABRA3 3159/4885GABRA2 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.