Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.66 |
| ▸ | PPIB | P23284 | 1/20 | 0.56 |
| ▸ | PPIA | P62937 | 1/20 | 0.56 |
| ▸ | PPIG | Q13427 | 1/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053656 | 0.81 | PPID (0.67) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL8526169 | 0.80 | PPID (0.61) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL12643825 | 0.80 | PPID (1.00) | PPIDPPIBPPIAPPIGEPHX2 | |
| SCHEMBL5444745 | 0.79 | KMT2A (0.51) | RIPK1ALDH1A1ANPEPKMT2AP2RX7 | |
| SCHEMBL15832182 | 0.78 | PPID (0.67) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL2036646 | 0.77 | PPID (0.74) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL2051574 | 0.76 | PPID (0.64) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL12643637 | 0.76 | PPID (0.56) | PPIDPPIBPPIAPPIGALDH1A1 | |
| Methylamine SCHEMBL8528191 | 0.76 | PPID (0.91) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL29511550 | 0.76 | PKM (0.53) | EPHX2ALDH1A1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249630-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
| US-20050209338-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | US | disclosed |
| EP-1478620-A1 | PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072539-A1 | PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209338-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | PHOSPHO1, PNMT, PEBP1 | PPID 3453/4885PPIB 3309/4885PPIA 3128/4885 |
| US-20070249630-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | PHOSPHO1, PNMT, PEBP1 | PPID 3453/4885PPIB 3309/4885PPIA 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.