Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.61 |
| ▸ | PPIB | P23284 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | PPIG | Q13427 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449507 | 0.80 | PPID (0.66) | PPIDPPIBPPIAPPIGNLRP3 | |
| SCHEMBL2053656 | 0.78 | PPID (0.67) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL7219075 | 0.78 | NLRP3 (0.55) | NLRP3ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL10065403 | 0.78 | P2RX7 (0.49) | ALDH1A1KDM4EGAAP2RX7POLB | |
| SCHEMBL12643825 | 0.76 | PPID (1.00) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL8138307 | 0.76 | PPID (0.69) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL6925202 | 0.76 | P2RX7 (0.49) | ALDH1A1KDM4EGAAL3MBTL1P2RX7 | |
| SCHEMBL15832182 | 0.75 | PPID (0.67) | PPIDPPIBPPIAPPIGNLRP3 | |
| SCHEMBL26661046 | 0.75 | CYP4F2 (0.63) | NLRP3ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL31036963 | 0.75 | P2RX7 (0.55) | ALDH1A1GAAL3MBTL1P2RX7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |