Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 6/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449732 | 0.99 | ALDH1A1 (0.73) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5477448 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL3988276 | 0.85 | ALDH1A1 (0.97) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5858139 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5858104 | 0.83 | RORC (0.51) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5859194 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5859249 | 0.82 | KIF11 (0.55) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5452093 | 0.82 | ALDH1A1 (0.95) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL8289801 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHRHPGDGAAHSD17B10 | |
| SCHEMBL5460139 | 0.81 | CFTR (0.60) | ALDH1A1TSHRHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | ALDH1A1 1153/4885TSHR 1038/4885HPGD 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.