Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463345 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CYP1A2CYP2C19GAASMN1; SMN2 | |
| SCHEMBL5450034 | 0.84 | GAA (0.76) | ALDH1A1GAASMN1; SMN2TDP1MAPT | |
| SCHEMBL6810538 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CYP1A2CYP2C19GAASMN1; SMN2 | |
| SCHEMBL17956756 | 0.83 | GAA (0.71) | ALDH1A1CYP1A2CYP2C19GAASMN1; SMN2 | |
| SCHEMBL5450035 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAASMN1; SMN2TDP1MAPT | |
| SCHEMBL1259295 | 0.81 | CYP1A2 (1.00) | ALDH1A1CYP1A2CYP2C19GAASMN1; SMN2 | |
| SCHEMBL6813674 | 0.81 | MEN1 (0.65) | ALDH1A1CYP1A2CYP2C19GAASMN1; SMN2 | |
| SCHEMBL30362755 | 0.80 | GAA (0.77) | ALDH1A1GAASMN1; SMN2MAPTALOX12 | |
| SCHEMBL28401851 | 0.80 | GAA (0.77) | ALDH1A1GAASMN1; SMN2MAPTALOX12 | |
| SCHEMBL8704828 | 0.79 | ALDH1A1 (0.66) | ALDH1A1CYP1A2CYP2C19GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | SERPINB1, CTRL, RNASE1 | ALDH1A1 1629/4885CYP1A2 1459/4885CYP2C19 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.