Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577413 | 0.86 | LMNA (0.61) | LMNAABCG2ALOX15TSHRHIF1A | |
| SCHEMBL6397903 | 0.83 | LMNA (0.57) | LMNAABCG2TSHRALDH1A1MAPT | |
| SCHEMBL27680965 | 0.81 | KMO (0.51) | LMNAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL16606388 | 0.80 | ABCG2 (0.53) | LMNAABCG2ALOX15ALDH1A1MAPT | |
| SCHEMBL11515085 | 0.77 | ABCG2 (0.48) | LMNAABCG2ALOX15ALDH1A1MAPT | |
| SCHEMBL11513769 | 0.75 | LMNA (0.70) | LMNAABCG2MAPTMAPK1ABCB1 | |
| SCHEMBL29020197 | 0.75 | MCL1 (0.55) | LMNAHIF1AALDH1A1MAPTKDM4E | |
| SCHEMBL29408221 | 0.75 | LMNA (0.47) | LMNAABCG2MAPTRXRAMAPK1 | |
| SCHEMBL22658241 | 0.75 | LMNA (0.47) | LMNAABCG2MAPTRXRAMAPK1 | |
| SCHEMBL27440256 | 0.75 | MGLL (0.47) | LMNAALDH1A1MAPTKDM4EKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ARAF, BRAF, RAF1 | LMNA 4138/4885ABCG2 71/4885NAPRT 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.