Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577413 | 0.84 | LMNA (0.61) | LMNAKDM4EKMT2ACYP1A2MAPT | |
| SCHEMBL4778479 | 0.84 | KMO (0.53) | KMOMKNK1MKNK2LMNAKDM4E | |
| SCHEMBL16606385 | 0.82 | ALDH1A1 (0.57) | LMNAKDM4EHTTKMT2ACYP2A6 | |
| SCHEMBL6397903 | 0.81 | LMNA (0.57) | LMNAKDM4EKMT2AALDH1A1CYP1A2 | |
| SCHEMBL5451011 | 0.81 | LMNA (0.45) | LMNAKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL15046260 | 0.81 | CYP2A6 (0.59) | LMNAKDM4EHTTKMT2ACYP2A6 | |
| SCHEMBL18104258 | 0.78 | CYP19A1 (0.57) | LMNAKDM4EHTTKMT2ACYP2A6 | |
| SCHEMBL4631312 | 0.78 | LMNA (0.67) | LMNAKDM4EHTTKMT2ACYP2A6 | |
| SCHEMBL19275973 | 0.78 | CYP19A1 (0.62) | LMNAKDM4EHTTKMT2ACYP2A6 | |
| SCHEMBL29808904 | 0.78 | CTRC (0.55) | KMOMKNK1MKNK2KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |