Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378167 | 0.94 | KMT2A (0.70) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA | |
| SCHEMBL3995356 | 0.94 | HRH3 (0.57) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA | |
| SCHEMBL13177083 | 0.93 | KMT2A (0.55) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2376571 | 0.90 | MAPT (0.68) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA | |
| SCHEMBL28783674 | 0.85 | ALDH1A1 (0.68) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA | |
| SCHEMBL3585157 | 0.84 | HRH3 (0.60) | KCNJ1MAPTSMN1; SMN2LMNAKCNH2 | |
| SCHEMBL3271959 | 0.83 | HRH3 (0.59) | KCNJ1MAPTSMN1; SMN2LMNAKCNH2 | |
| SCHEMBL4951837 | 0.83 | ALDH1A1 (0.73) | KMT2AMAPTSMN1; SMN2ALDH1A1GLA | |
| SCHEMBL9388850 | 0.82 | KMT2A (0.48) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL9383787 | 0.82 | KMT2A (0.47) | KMT2AKCNJ1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734179-B1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO KGAA (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20140245541-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-09-04 | — | — | US | disclosed |
| US-8821592-B1 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140245541-A1 | NOVEL OXIDATION DYE PRECURSORS | KRT18, SQOR, NDUFA5 | KMT2A 2058/4885KCNJ1 699/4885MAPT 844/4885 |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | KRT18, CDC73, AOC1 | KMT2A 1573/4885KCNJ1 1305/4885MAPT 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.