SCHEMBL545113

SCHEMBL545113

C=CC[Si](Oc1ccccc1)(Oc1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.32
KCNA3 P22001 1/20 0.31
LTA4H P09960 1/20 0.31
TSHR P16473 1/20 0.31
MMP9 P14780 1/20 0.31
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109862 0.78 ACHE (0.33) SMN1; SMN2MEN1KMT2ATSHRGAA
SCHEMBL9260850 0.78 TSHR (0.35) SMN1; SMN2KDM4EMEN1KMT2ATHRB
SCHEMBL1427919 0.78 TSHR (0.35) SMN1; SMN2KDM4EMEN1KMT2ATHRB
SCHEMBL5405196 0.78 TSHR (0.35) SMN1; SMN2KDM4EMEN1KMT2ATHRB
SCHEMBL704165 0.77 LTA4H (0.38) SMN1; SMN2KCNA3LTA4HTSHRHTT
SCHEMBL705116 0.77 LTA4H (0.38) SMN1; SMN2KDM4EKMT2AKCNA3LTA4H
SCHEMBL72196 0.76 MEN1 (0.32) MEN1KMT2A
SCHEMBL15266830 0.76
SCHEMBL13822383 0.74 CA4 (0.34) SMN1; SMN2KDM4EMEN1KMT2ATHRB
SCHEMBL1493061 0.74 MEN1 (0.33) SMN1; SMN2KDM4EMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10875879-B2 Compositions, synthesis, and uses of hydrolyzable silane modified cashew nut shell liquid derivatives CARDOLITE CORPORATION (US) 2020-12-29 US claimed
US-20190077815-A1 COMPOSITIONS, SYNTHESIS, AND USES OF HYDROLYZABLE SILANE MODIFIED CASHEW NUT SHELL LIQUID DERIVATIVES CARDOLITE CORPORATION 2019-03-14 US claimed
US-8110036-B2 Moisture curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERISTY (US) 2012-02-07 US claimed
WO-2010042175-A1 MOISTURE-CURABLE OIL AND FAT COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME MICHIGAN STATE UNIVERSITY (US) 2010-04-15 WO claimed
US-20100083871-A1 Moisture-curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-04-08 US claimed
US-11912889-B2 Silicon-containing polymer, film-forming composition, method for forming silicon-containing polymer coating, method for forming silica coating, and production method for silicon-containing polymer TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-27 US disclosed
US-20220220338-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR FORMING SILICON-CONTAINING POLYMER COATING, METHOD FOR FORMING SILICA COATING, AND PRODUCTION METHOD FOR SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-14 US disclosed
US-20220213348-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-07 US disclosed
US-11377522-B2 Silicon-containing polymer, film-forming composition, method for forming silicon-containing polymer coating, method for forming silica-based coating, and production method for silicon-containing polymer TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-05 US disclosed
EP-3971229-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR FORMING SILICON-CONTAINING POLYMER COATING, METHOD FOR FORMING SILICA COATING, AND PRODUCTION METHOD FOR SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-03-23 EP disclosed
EP-3957678-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER Tokyo Ohka Kogyo Co., Ltd. (JP) 2022-02-23 EP disclosed
US-10875879-B2 Compositions, synthesis, and uses of hydrolyzable silane modified cashew nut shell liquid derivatives CARDOLITE CORPORATION (US) 2020-12-29 US disclosed
US-8110036-B2 Moisture curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERISTY (US) 2012-02-07 US disclosed
WO-2010042175-A1 MOISTURE-CURABLE OIL AND FAT COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME MICHIGAN STATE UNIVERSITY (US) 2010-04-15 WO disclosed
US-20100083871-A1 Moisture-curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-04-08 US disclosed
US-4512926-A Process for the silylation of unsaturated, naturally occurring oils or the interesterification products thereof CHEMISCHE WERKE HUELS AG (DE) 1985-04-23 US disclosed
EP-0069216-B1 PROCESS FOR THE SILYLATION OF NATURAL UNSATURATED OILS, AND THEIR TRANSESTERIFICATION PRODUCTS HÜLS AKTIENGESELLSCHAFT (DE) 1985-03-27 EP disclosed
US-4396751-A Homo- and copolymers of 1,3-dienes containing reactive silyl groups, and their preparation and use CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) 1983-08-02 US disclosed
US-4381377-A Homo- or copolymers of 1,3-dienes carrying reactive silyl groups, their preparation and use CHEMISCHE WERKE HUELS, AG (DE) 1983-04-26 US disclosed
EP-0069216-A1 Process for the silylation of natural unsaturated oils, and their transesterification products HÜLS AKTIENGESELLSCHAFT (DE) 1983-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077815-A1 COMPOSITIONS, SYNTHESIS, AND USES OF HYDROLYZABLE SILANE MODIFIED CASHEW NUT SHELL LIQUID DERIVATIVES NANS, SGMS1, FUT6 SMN1; SMN2 3374/4885KDM4E 2229/4885MEN1 1764/4885
US-10875879-B2 Compositions, synthesis, and uses of hydrolyzable silane modified cashew nut shell liquid derivatives NANS, SGMS1, FUT6 SMN1; SMN2 3374/4885KDM4E 2229/4885MEN1 1764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.