Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473516 | 0.84 | MAPT (0.54) | RBP4MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5465924 | 0.83 | KDM4E (0.46) | MAPTALDH1A1KDM4ETRPV1USP2 | |
| SCHEMBL5473181 | 0.82 | RBP4 (0.47) | RBP4MAPTALDH1A1KDM4ETRPV1 | |
| SCHEMBL5463477 | 0.82 | TRPV1 (0.53) | RBP4MAPTALDH1A1TRPV1SMN1; SMN2 | |
| SCHEMBL5464794 | 0.81 | GFER (0.59) | RBP4MAPTALDH1A1KDM4ETRPV1 | |
| SCHEMBL5467111 | 0.81 | MAPT (0.51) | RBP4MAPTALDH1A1KDM4ETRPV1 | |
| SCHEMBL5460059 | 0.80 | MAPT (0.50) | RBP4MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5465645 | 0.79 | CNR1 (0.52) | MAPTKDM4EIGF1RRAB9ACNR1 | |
| SCHEMBL5459635 | 0.79 | MAPK1 (0.51) | MAPTALDH1A1KDM4ETRPV1TSHR | |
| SCHEMBL16690815 | 0.78 | MAPT (0.78) | RBP4MAPTALDH1A1KDM4ETRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | RBP4 2001/4885MAPT 758/4885ALDH1A1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.