Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459861 | 0.90 | MAPT (0.50) | MAPK1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL5465924 | 0.85 | KDM4E (0.46) | MAPK1KDM4ESMN1; SMN2HTTHSD17B10 | |
| SCHEMBL5455745 | 0.84 | DGAT1 (0.54) | MAPK1KDM4ESMN1; SMN2HTTHSD17B10 | |
| SCHEMBL5467383 | 0.80 | MAPT (0.56) | MAPK1SMN1; SMN2HTTLMNAP2RY12 | |
| SCHEMBL5460864 | 0.80 | WNT3A (0.54) | MAPK1KDM4ESMN1; SMN2HTTHSD17B10 | |
| SCHEMBL5466996 | 0.79 | DGAT1 (0.55) | MAPK1KDM4ESMN1; SMN2HTTHSD17B10 | |
| SCHEMBL5451482 | 0.79 | RBP4 (0.58) | MAPK1KDM4ESMN1; SMN2HSD17B10MAPT | |
| SCHEMBL5454288 | 0.78 | MEN1 (0.49) | MAPK1KDM4ESMN1; SMN2HTTHSD17B10 | |
| SCHEMBL5454381 | 0.76 | NPC1 (0.47) | MAPK1KDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5456882 | 0.75 | MAPT (0.49) | MAPK1KDM4ESMN1; SMN2KITMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | MAPK1 1466/4885KDM4E 2284/4885SMN1; SMN2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.