Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459030 | 0.84 | TLR7 (0.51) | LMNATLR7POLBHRH2ADRA1D | |
| SCHEMBL2040358 | 0.82 | LMNA (0.60) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5808827 | 0.78 | LMNA (0.53) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL6722237 | 0.78 | SMN1; SMN2 (0.45) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL6723854 | 0.78 | NPSR1 (0.52) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL6726678 | 0.76 | ALDH1A1 (0.39) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL6724014 | 0.76 | SMN1; SMN2 (0.47) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL6722346 | 0.75 | TLR7 (0.40) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL6724108 | 0.75 | ALDH1A1 (0.39) | LMNAALDH1A1SMN1; SMN2TLR7POLB | |
| SCHEMBL10739564 | 0.75 | ALDH1A1 (0.64) | LMNAALDH1A1SMN1; SMN2TLR7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | IL2, IL4, IRF3 | LMNA 4207/4885ALDH1A1 2134/4885SMN1; SMN2 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.