Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042201 | 0.88 | NPSR1 (0.55) | LMNAGAAALDH1A1KDM4ERAB9A | |
| SCHEMBL2043288 | 0.86 | GAA (0.58) | LMNAGAAALDH1A1TSHRHDAC1 | |
| SCHEMBL2040172 | 0.86 | ALDH1A1 (0.52) | LMNAALDH1A1KDM4EHTTHPGD | |
| SCHEMBL2042632 | 0.83 | HPGD (0.56) | LMNAGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL5451784 | 0.82 | LMNA (0.42) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL2039016 | 0.81 | ALDH1A1 (0.46) | GAAALDH1A1KDM4EHTTTSHR | |
| SCHEMBL5459030 | 0.79 | TLR7 (0.51) | LMNA | |
| SCHEMBL2043795 | 0.75 | ACSS2 (0.49) | GAAKDM4EHTTRAB9AHPGD | |
| SCHEMBL18250343 | 0.74 | LMNA (0.65) | LMNAGAAALDH1A1KDM4EHTT | |
| SCHEMBL2041269 | 0.74 | GAA (0.44) | GAAHDAC1HDAC6MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |