Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343101 | 0.83 | WDR5 (0.42) | KDM4EALDH1A1HPGDGLAMEN1 | |
| SCHEMBL5450046 | 0.81 | ADRB2 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11636414 | 0.78 | HCAR2 (0.39) | KDM4EALDH1A1HPGDGLAMEN1 | |
| SCHEMBL13159363 | 0.78 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDGLAMEN1 | |
| SCHEMBL301790 | 0.77 | TSHR (0.43) | KDM4EALDH1A1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL434162 | 0.76 | TSHR (0.49) | ALDH1A1MEN1KMT2ACYP1A2LMNA | |
| SCHEMBL8982606 | 0.75 | RAB9A (0.42) | ALDH1A1MEN1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL14440746 | 0.74 | THRB (0.51) | KDM4EALDH1A1HPGDGLAMEN1 | |
| SCHEMBL1561008 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5452453 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1HPGDGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149440-B2 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-10-06 | — | — | US | disclosed |
| US-20070190160-A1 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA | 2007-08-16 | — | — | US | disclosed |
| WO-2005020933-A2 | NANOPARTICLES FOR DRUG-DELIVERY | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190160-A1 | Nanoparticles for drug-delivery | EPCAM, TUBB1, ACTB | KDM4E 4213/4885ALDH1A1 897/4885HPGD 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.