Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237031 | 1.00 | RIPK1 (0.52) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL42066 | 0.82 | HRH1 (0.62) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL232834 | 0.82 | HRH1 (0.62) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL3179795 | 0.82 | HRH1 (0.62) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL5185803 | 0.81 | RIPK1 (0.64) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL3081755 | 0.81 | RIPK1 (0.64) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL2157996 | 0.80 | CPN1 (0.44) | AOC3LMNAKDM4ETAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL4374172 | 0.80 | HRH1 (0.60) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16032107 | 0.80 | HRH1 (0.60) | RIPK1AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL7417534 | 0.80 | HRH1 (0.68) | RIPK1AOC3LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032555-A1 | Novel aryloxyphenyl-propanamines | CONCERT PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032555-A1 | Novel aryloxyphenyl-propanamines | SLC6A2, SLC6A3, SLC18A1 | RIPK1 4858/4885AOC3 306/4885LMNA 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.