SCHEMBL5452714

SCHEMBL5452714

CCN(CC)c1ccc(C)c(NC(=S)Nc2ccc(Cl)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
GAA P10253 5/20 0.58
ALDH1A1 P00352 5/20 0.58
KDM4E B2RXH2 2/20 0.58
MAPK1 P28482 2/20 0.58
THRB P10828 1/20 0.58
HTT P42858 1/20 0.58
KMT2A Q03164 4/20 0.47
NOX1 Q9Y5S8 1/20 0.47
MEN1 O00255 3/20 0.47
CNR2 P34972 1/20 0.47
CNR1 P21554 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5452704 0.90 ALDH1A1 (0.58) MAPTGAAALDH1A1KDM4EMAPK1
SCHEMBL6441154 0.82 ALDH1A1 (0.68) MAPTGAAALDH1A1KDM4EMAPK1
SCHEMBL13560846 0.78 ALDH1A1 (0.56) MAPTGAAALDH1A1KDM4EMAPK1
SCHEMBL2465333 0.77 KMT2A (0.69) MAPTGAAALDH1A1KDM4EMAPK1
SCHEMBL3713566 0.76 S100B (0.47) MAPTGAAALDH1A1KDM4EMAPK1
SCHEMBL2467293 0.75 MEN1 (0.66) MAPTGAAALDH1A1KDM4EMAPK1
SCHEMBL6811254 0.73 KMT2A (0.69) MAPTGAAALDH1A1KDM4EKMT2A
SCHEMBL13741135 0.72 MAPT (0.48) MAPTGAAALDH1A1MAPK1HTT
SCHEMBL26418393 0.72 GHSR (0.53) MAPTGAAALDH1A1MAPK1HTT
SCHEMBL7913697 0.71 S100B (0.41) MAPTGAAALDH1A1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed