Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21406016 | 0.89 | ALOX5 (0.54) | ALOX5CYP2A6MAOAMAOBCYP3A4 | |
| SCHEMBL18003399 | 0.83 | MAPT (0.60) | MAOAMAOBMAPTL3MBTL1MRGPRX4 | |
| SCHEMBL17338671 | 0.81 | ALOX5 (0.51) | ALOX5MAOAMAOBCYP3A4NPC1 | |
| SCHEMBL9136135 | 0.78 | ALOX5 (0.58) | ALOX5MAOAMAOBCYP3A4NPC1 | |
| SCHEMBL27970437 | 0.78 | ALOX5 (0.58) | ALOX5MAOAMAOBCYP3A4NPC1 | |
| SCHEMBL27643424 | 0.78 | ALOX5 (0.58) | ALOX5MAOAMAOBCYP3A4NPC1 | |
| SCHEMBL17338662 | 0.78 | ALOX5 (0.48) | ALOX5MAOAMAOBCYP3A4NPC1 | |
| SCHEMBL17347192 | 0.78 | NR4A2 (0.54) | ALOX5CYP3A4MEN1KMT2ACA12 | |
| SCHEMBL6807350 | 0.77 | ALOX5 (0.57) | ALOX5MAOAMAOBCYP3A4NPC1 | |
| SCHEMBL27664686 | 0.77 | ALOX5 (0.57) | ALOX5MAOAMAOBCYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-3774764-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | Merck Sharp&Dohme Corp. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-111971277-A | Benzothiophenes and related compounds as STING agonists | 默沙东公司 | 2020-11-20 | — | — | CN | disclosed |
| US-10793557-B2 | Sting agonist compounds | MERCK SHARP & DOHME CORP. (US) | 2020-10-06 | — | — | US | disclosed |
| US-10793557-B2 | Sting agonist compounds | MERCK SHARP & DOHME CORP. (US) | 2020-10-06 | — | — | US | disclosed |
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |
| US-20190300513-A1 | STING AGONIST COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-10-03 | — | — | US | disclosed |
| US-20190300513-A1 | STING AGONIST COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-10-03 | — | — | US | disclosed |
| CN-1890221-B | 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them | THERAMEX | 2014-07-16 | — | — | CN | disclosed |
| US-8476455-B2 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2013-07-02 | — | — | US | disclosed |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2007-05-17 | — | — | US | disclosed |
| CN-1890221-A | 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them | THERAMEX (MC) | 2007-01-03 | — | — | CN | disclosed |
| EP-1694650-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058842-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300513-A1 | STING AGONIST COMPOUNDS | STING1, CGAS, IRF3 | ALOX5 2004/4885CYP2A6 3504/4885MAOA 3065/4885 |
| US-10793557-B2 | Sting agonist compounds | STING1, CGAS, IRF3 | ALOX5 2004/4885CYP2A6 3504/4885MAOA 3065/4885 |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | H1-0, H1-5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALOX5 3744/4885CYP2A6 264/4885MAOA 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.