Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551981 | 0.83 | TSHR (0.64) | VCAM1MAPTNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL30923019 | 0.83 | TSHR (0.64) | VCAM1MAPTNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL11691947 | 0.81 | MAPT (0.54) | VCAM1MAPTMITFRECQLRAB9A | |
| SCHEMBL213758 | 0.80 | TSHR (0.56) | NPSR1ALDH1A1CYP3A4GPR35MAPK1 | |
| SCHEMBL29577003 | 0.80 | TSHR (0.56) | NPSR1ALDH1A1CYP3A4GPR35MAPK1 | |
| SCHEMBL69947 | 0.78 | MAPK1 (0.67) | MAPTRAB9AALDH1A1CYP3A4LMNA | |
| SCHEMBL358730 | 0.78 | MAPK1 (0.69) | VCAM1ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL6796101 | 0.78 | ESR1 (0.57) | MAPTALDH1A1GPR35MAPK1TSHR | |
| SCHEMBL6031674 | 0.78 | MAPK1 (0.67) | MAPTRAB9AALDH1A1CYP3A4LMNA | |
| SCHEMBL5992360 | 0.78 | VCAM1 (0.60) | VCAM1MAPTALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702390-B | Preparation method of 4-chloro-3-nitroanisole | 常州佳德医药科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| US-20220372008-A1 | LUCIFERIN DERIVATIVES AND A METHOD FOR SYNTHESIS THEREOF | VIDYASIRIMEDHI INSTITUTE OF SCIENCE AND TECHNOLOGY (TH) | 2022-11-24 | — | — | US | claimed |
| CN-114702390-A | Preparation method of 4-chloro-3-nitrobenzyl ether | 常州佳德医药科技有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-109956895-A | A kind of procymidone haptens and its synthetic method and application | 深圳市易瑞生物技术股份有限公司 | 2019-07-02 | — | — | CN | claimed |
| CN-106336385-B | The synthetic method of Yi Zhong Evil humulones | 江苏丰华化学工业有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-105621587-B | A kind of method using potentiometric titrations degradating chloro nitro-aromatic | 浙江大学 | 2018-01-23 | — | — | CN | claimed |
| CN-105646231-B | A kind of preparation method of the nitrophenol of 2,4 dichloro 5 | 连云港市金囤农化有限公司 | 2017-09-22 | — | — | CN | claimed |
| CN-106336385-A | Oxadiazon synthesis method | 江苏丰华化学工业有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-105837402-A | Preparation method for 2,4-dichloro-5-bromotoluene | 常州大学 | 2016-08-10 | — | — | CN | claimed |
| CN-105753730-A | Method for preparing 2-amino-4-chloro-5-nitrophenol | 宜兴市新宇化工有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-105646231-A | Method for preparing 2,4-dichloro-5-nitrophenol | 连云港市金囤农化有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-105621587-A | Method for degrading chloro-nitroaromatic by using sulfate radicals | UNIV ZHEJIANG | 2016-06-01 | — | — | CN | claimed |
| CN-102295838-B | Six-branched azosiloxane dye and synthesis method thereof | ZHEJIANG UNIVERSITY (CN) | 2014-10-08 | — | — | CN | claimed |
| CN-1271027-C | Method of synthesizing dihalogenated aromatic ether by phase transfer | JIAXING COLLEGE (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-1651380-A | Method of synthesizing dihalogenated aromatic ether by phase transfer | JIAXING COLLEGE (CN) | 2005-08-10 | — | — | CN | claimed |
| EP-0299891-B1 | PROCESS FOR THE SELECTIVE CHLORINATION OF PHENOLIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0299891-A1 | Process for the selective chlorination of phenolic compounds | RHONE-POULENC CHIMIE (FR) | 1989-01-18 | — | — | EP | claimed |
| EP-3704094-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| US-4000270-A | INSECTIDES, ACARICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3954919-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220372008-A1 | LUCIFERIN DERIVATIVES AND A METHOD FOR SYNTHESIS THEREOF | NQO1, DDT, GLO1 | VCAM1 2891/4885MAPT 3290/4885MITF 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.