Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404933 | 1.00 | TAS1R3 (0.49) | TAS1R3TAS1R1PLK1PPARGPOLB | |
| SCHEMBL399540 | 1.00 | TAS1R3 (0.49) | TAS1R3TAS1R1PLK1PPARGPOLB | |
| SCHEMBL403007 | 0.96 | PLK1 (0.53) | TAS1R3TAS1R1PLK1PPARGPOLB | |
| SCHEMBL405496 | 0.93 | PPARG (0.52) | PLK1PPARGALDH1A1 | |
| SCHEMBL1912153 | 0.91 | PPARG (0.54) | PLK1PPARGALDH1A1 | |
| SCHEMBL404416 | 0.90 | PLK1 (0.56) | TAS1R3TAS1R1PLK1POLBCTDSP1 | |
| SCHEMBL400177 | 0.90 | TAS1R3 (0.50) | TAS1R3TAS1R1PLK1PPARGNPC1 | |
| SCHEMBL30132213 | 0.89 | ACACB (0.51) | PPARGACACB | |
| SCHEMBL1096679 | 0.89 | CA2 (0.42) | PPARGANPEP | |
| SCHEMBL403324 | 0.89 | TAS1R3 (0.48) | TAS1R3TAS1R1PLK1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | TAS1R3 4169/4885TAS1R1 3477/4885PLK1 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.