Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.95 |
| ▸ | HPGD | P15428 | 11/20 | 0.95 |
| ▸ | MAPT | P10636 | 10/20 | 0.95 |
| ▸ | RAB9A | P51151 | 6/20 | 0.95 |
| ▸ | NPC1 | O15118 | 6/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.95 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.79 |
| ▸ | USP2 | O75604 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290734 | 0.98 | HPGD (1.00) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL3913354 | 0.85 | HPGD (0.78) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL5460090 | 0.85 | ALDH1A1 (0.74) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL8288728 | 0.84 | ALDH1A1 (1.00) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL3916266 | 0.83 | NPC1 (1.00) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL5449432 | 0.82 | ALDH1A1 (1.00) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL16210883 | 0.82 | KIF11 (0.98) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL16211025 | 0.82 | ALDH1A1 (0.72) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL17916667 | 0.81 | HPGD (0.70) | FLT3ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL8290847 | 0.81 | NPC1 (0.80) | FLT3ALDH1A1HPGDMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171603-A1 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor | VICHEM CHEMIE KFT (HU) | 2004-09-02 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | FLT3 3509/4885ALDH1A1 1153/4885HPGD 2361/4885 |
| US-20040171603-A1 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor | PKLR, PKN1, PKMYT1 | FLT3 1906/4885ALDH1A1 4655/4885HPGD 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.