Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449907 | 0.89 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5452558 | 0.89 | EPHX1 (0.56) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5452802 | 0.87 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5456707 | 0.85 | MEN1 (0.51) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL12225791 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5447964 | 0.83 | GRM1 (0.51) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL5448199 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5446600 | 0.77 | ALDH1A1 (0.78) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5456442 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AMEN1GAAKDM4E | |
| SCHEMBL5445578 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |