Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456707 | 0.89 | MEN1 (0.51) | ALDH1A1MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL5453556 | 0.87 | SMN1; SMN2 (0.52) | ALDH1A1MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL5449907 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL5452558 | 0.84 | EPHX1 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL5445865 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1MAPTSMN1; SMN2LMNASIRT1 | |
| SCHEMBL12067341 | 0.79 | SIRT1 (0.71) | ALDH1A1MAPTSMN1; SMN2LMNASIRT1 | |
| SCHEMBL5447964 | 0.79 | GRM1 (0.51) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL5456442 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL2344788 | 0.77 | KMT2A (0.68) | ALDH1A1MAPTSMN1; SMN2LMNASIRT1 | |
| SCHEMBL12940302 | 0.77 | SIRT1 (0.65) | ALDH1A1MAPTSMN1; SMN2LMNASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |