Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.55 |
| ▸ | CCR6 | P51684 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456707 | 0.86 | MEN1 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14096561 | 0.78 | MEN1 (0.59) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5452802 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14096446 | 0.77 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5449907 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5453556 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5447964 | 0.76 | GRM1 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14096364 | 0.76 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4362081 | 0.75 | MEN1 (0.49) | SMN1; SMN2RXFP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5452558 | 0.74 | EPHX1 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |