Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453556 | 0.89 | SMN1; SMN2 (0.52) | ALDH1A1NPSR1NPC1RAB9AMAPT | |
| SCHEMBL5449907 | 0.86 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMAPTALOX12 | |
| SCHEMBL5447964 | 0.86 | GRM1 (0.51) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5452802 | 0.84 | ALDH1A1 (0.52) | ALDH1A1NPSR1NPC1RAB9AMAPT | |
| SCHEMBL5456707 | 0.83 | MEN1 (0.51) | ALDH1A1NPSR1NPC1RAB9AMAPT | |
| SCHEMBL5446625 | 0.81 | SMN1; SMN2 (0.60) | EPHX1ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL5448328 | 0.75 | RAB9A (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5448199 | 0.75 | ALDH1A1 (0.59) | EPHX1ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL5456442 | 0.74 | SMN1; SMN2 (0.58) | ALDH1A1NPSR1MAPTALOX12SMN1; SMN2 | |
| SCHEMBL5445578 | 0.74 | ALDH1A1 (0.58) | EPHX1ALDH1A1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |