Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847829 | 0.91 | CA9 (0.38) | CA9CA1CA2CA6CA5A | |
| SCHEMBL31215617 | 0.81 | CA9 (0.36) | CA9CA1CA2CA6CA5A | |
| SCHEMBL27427442 | 0.79 | ALOX15 (0.42) | CA9CA1CA2CA6CA5A | |
| SCHEMBL1266166 | 0.79 | ALOX15 (0.42) | CA9CA1CA2CA6CA5A | |
| SCHEMBL1134914 | 0.77 | ALOX15 (0.40) | CA9CA1CA2CA6CA5A | |
| SCHEMBL29547583 | 0.77 | ALOX15 (0.40) | CA9CA6CA5ACA14CA5B | |
| SCHEMBL29365100 | 0.77 | ALDH1A1 (0.46) | CA9CA1CA2CA6CA5A | |
| SCHEMBL29501763 | 0.77 | ALOX15 (0.40) | CA9CA1CA2CA6CA5A | |
| SCHEMBL275963 | 0.77 | ALDH1A1 (0.46) | CA9CA1CA2CA6CA5A | |
| SCHEMBL6659815 | 0.77 | ALDH1A1 (0.40) | CA9CA1CA2CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3223821-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-10-04 | — | — | EP | disclosed |
| US-20170253602-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-07 | — | — | US | disclosed |
| WO-2016083276-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-02 | — | — | WO | disclosed |
| US-20070066633-A1 | Quinazoline compounds | ASTRAZENECA AB | 2007-03-22 | — | — | US | disclosed |
| US-7160889-B2 | Quinazoline compounds | ASTRAZENECA AB (SE) | 2007-01-09 | — | — | US | disclosed |
| US-7087602-B2 | Cinnoline derivatives and use as medicine | ASTRAZENECA UK LIMITED (GB) | 2006-08-08 | — | — | US | disclosed |
| EP-1274692-B1 | QUINAZOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | EP | disclosed |
| CN-1252054-C | Qinoline derivatives inhibiting effect of growth factors such as VEGF | ZENECA LTD (GB) | 2006-04-19 | — | — | CN | disclosed |
| CN-1240688-C | Quinazoline compounds | ASTRAZENECA AB (SE) | 2006-02-08 | — | — | CN | disclosed |
| EP-0888310-B1 | CINNOLINE DERIVATIVES AND USE AS MEDICINE | ASTRAZENECA AB (SE) | 2005-09-07 | — | — | EP | disclosed |
| US-4826533-A | IN CORN AND SOYBEAN FIELDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4770695-A | CORN OR SOYABEAN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-13 | — | — | US | disclosed |
| US-4736068-A | Tetrahydrophthalimides and their production and use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0083055-B1 | TETRAHYDROPHTHALIMIDE COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0061741-B1 | TETRAHYDROPHTHALIMIDES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4484941-A | Tetrahydrophthalimides, and their production and use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-27 | — | — | US | disclosed |
| US-4484940-A | Tetrahydrophthalimides, and their production and use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-27 | — | — | US | disclosed |
| US-4431822-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-02-14 | — | — | US | disclosed |
| EP-0083055-A2 | Tetrahydrophthalimide compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-06 | — | — | EP | disclosed |
| EP-0061741-A2 | Tetrahydrophthalimides, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253602-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BDKRB2, BDKRB1, PDGFRB | CA9 3926/4885CA1 4427/4885CA2 3455/4885 |
| US-20070066633-A1 | Quinazoline compounds | CCR7, CNR1, CBR3 | CA9 681/4885CA1 1150/4885CA2 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.