Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453603 | 0.91 | CA9 (0.38) | CA9CA1CA2CA6CA5A | |
| SCHEMBL741941 | 0.81 | ALDH1A1 (0.37) | CA9CA1CA2CA12ALOX15 | |
| SCHEMBL30193870 | 0.81 | ALDH1A1 (0.37) | CA9CA1CA2CA12ALOX15 | |
| SCHEMBL1266166 | 0.79 | ALOX15 (0.42) | CA9CA1CA2CA6CA5A | |
| SCHEMBL27427442 | 0.79 | ALOX15 (0.42) | CA9CA1CA2CA6CA5A | |
| Hydrochloric Acid SCHEMBL16893994 | 0.79 | KDM4E (0.35) | CA9CA1CA2CA12ALOX15 | |
| SCHEMBL350192 | 0.77 | ALDH1A1 (0.40) | CA9CA1CA2CA6CA5A | |
| SCHEMBL1529272 | 0.77 | ALDH1A1 (0.46) | CA9CA1CA2CA6CA5A | |
| SCHEMBL29703386 | 0.77 | ALDH1A1 (0.46) | CA9CA1CA2CA6CA5A | |
| SCHEMBL139113 | 0.77 | CA6 (0.40) | CA9CA1CA2CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-12 | — | — | US | claimed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | claimed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | claimed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | claimed |
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-7358397-B2 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | disclosed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| US-5132325-A | BENZOYLPHENYLUREAS THE PREPARATION THEREOF AND THE USE THEREOF IN PEST CONTROL | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0235089-B1 | N-BENZOYL-N'-PHENYL UREAS, THEIR PREPARATION AND THEIR USE AGAINST PESTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| EP-0432135-A1 | Intermediates for benzoylphenyl ureas | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| CN-87100956-A | The preparation method of N-benzoyl-N '-phenyl ureas | — | 1987-09-09 | — | — | CN | disclosed |
| EP-0235089-A2 | N-benzoyl-N'-phenyl ureas, their preparation and their use against pests | CIBA-GEIGY AG (CH) | 1987-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, CYP4B1, PAH | CA9 3160/4885CA1 4498/4885CA2 3712/4885 |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, HPD, CYP4F8 | CA9 2664/4885CA1 4576/4885CA2 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.