Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456052 | 0.91 | PKM (0.43) | KMT2A | |
| SCHEMBL5438443 | 0.90 | GAA (0.42) | KMT2A | |
| SCHEMBL5443229 | 0.87 | TACR1 (0.36) | — | |
| SCHEMBL5446694 | 0.87 | MAOB (0.35) | — | |
| SCHEMBL5449425 | 0.86 | AKR1B1 (0.33) | WDR5KMT2A | |
| SCHEMBL5452304 | 0.84 | ALDH1A1 (0.34) | KMT2A | |
| SCHEMBL5440602 | 0.83 | MAOB (0.41) | KMT2A | |
| SCHEMBL5457538 | 0.83 | MMP10 (0.35) | KMT2A | |
| SCHEMBL5445142 | 0.83 | EGLN1 (0.39) | KMT2A | |
| SCHEMBL5450208 | 0.83 | EGLN1 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179196-A1 | Hiv integrase inhibitors | MERCK SHARP & DOHME CORP. | 2007-08-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179196-A1 | Hiv integrase inhibitors | REV1, TYMP, POLR2H | WDR5 1380/4885KMT2A 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.