Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 14/20 | 0.70 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.64 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.64 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456487 | 0.83 | KCNN3 (0.73) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL5453886 | 0.82 | CDK2 (0.55) | KCNN3KCNN1KCNN2 | |
| SCHEMBL5468148 | 0.80 | KCNN3 (0.47) | KCNN3KCNN1KCNN2PDE10ATUBB4A | |
| SCHEMBL5451856 | 0.80 | CDK2 (0.52) | KCNN3KCNN1KCNN2 | |
| SCHEMBL5454745 | 0.79 | CDK2 (0.47) | KCNN3KCNN1KCNN2PDE10ATUBB4A | |
| SCHEMBL5449800 | 0.79 | CDK2 (0.47) | KCNN3KCNN1KCNN2TUBB4ATUBB | |
| SCHEMBL5451924 | 0.79 | KCNN3 (0.48) | KCNN3KCNN1KCNN2TUBB4ATUBB | |
| SCHEMBL13117302 | 0.78 | KCNN3 (0.80) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL5447997 | 0.78 | CDK2 (0.53) | KCNN3KCNN1KCNN2 | |
| SCHEMBL902740 | 0.76 | KCNN3 (0.67) | KCNN3KCNN1KCNN2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | JUN, CHUK, RELA | KCNN3 3885/4885KCNN1 3422/4885KCNN2 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.