Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.54 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.42 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451856 | 0.89 | CDK2 (0.52) | CDK2CCNE1KCNN3GAAPIK3CG | |
| SCHEMBL5454745 | 0.89 | CDK2 (0.47) | CDK2CCNE1KCNN3GAAPIK3CG | |
| SCHEMBL5449800 | 0.86 | CDK2 (0.47) | CDK2CCNE1KCNN3GAAPIK3CG | |
| SCHEMBL5447997 | 0.85 | CDK2 (0.53) | CDK2CCNE1KCNN3PIK3CGBRAF | |
| SCHEMBL5468148 | 0.83 | KCNN3 (0.47) | CDK2CCNE1KCNN3GAAKCNN1 | |
| SCHEMBL5451924 | 0.82 | KCNN3 (0.48) | CDK2CCNE1KCNN3GAAKCNN1 | |
| SCHEMBL5453724 | 0.82 | KCNN3 (0.70) | KCNN3KCNN1KCNN2 | |
| SCHEMBL5454018 | 0.78 | CDK2 (0.67) | CDK2CCNE1KCNN3KCNN1KCNN2 | |
| SCHEMBL5451908 | 0.77 | CDK2 (0.72) | CDK2CCNE1KCNN3KCNN1KCNN2 | |
| SCHEMBL5455497 | 0.76 | CDK2 (0.64) | CDK2CCNE1KCNN3KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | claimed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | claimed |
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | JUN, CHUK, RELA | CDK2 284/4885CCNE1 223/4885KCNN3 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.