Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460636 | 0.84 | CYP19A1 (0.51) | FDPSCYP2D6CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL6981682 | 0.79 | CYP19A1 (0.45) | ALDH1A1SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL5849664 | 0.78 | CYP3A4 (0.51) | SIGMAR1FDPSGAAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL5848397 | 0.77 | CYP3A4 (0.50) | SIGMAR1FDPSGAAALDH1A1POLB | |
| SCHEMBL3758352 | 0.72 | TBXAS1 (0.56) | GAAPOLBGRM2CYP2D6CYP1A2 | |
| SCHEMBL6176772 | 0.72 | CHRNA7 (0.57) | GAAPOLBGRM2CYP2D6CYP1A2 | |
| SCHEMBL4726907 | 0.72 | FDPS (0.56) | FDPSALDH1A1CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL9985184 | 0.72 | CYP19A1 (0.42) | ALDH1A1POLBCYP2D6CYP3A4CYP19A1 | |
| SCHEMBL2096123 | 0.72 | FDPS (0.51) | FDPSALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL27560189 | 0.72 | CYP19A1 (0.42) | ALDH1A1POLBCYP2D6CYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | claimed |
| CN-1213044-C | Amine and amide derivatives as ligands of the neuropeptide YY5 receptor for the treatment of obesity and other diseases | ORTHO MCNEIL PHARM INC (US) | 2005-08-03 | — | — | CN | disclosed |
| CN-1382135-A | Amine and amide derivatives as ligands for neuropeptide YY5 receptor usefu in treatment of obesity and other disorders | ORTHO MCNEIL PHARM INC (US) | 2002-11-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | MAVS, SARS1, ZC3HAV1 | SIGMAR1 3190/4885FDPS 1038/4885GAA 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.