Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403877 | 0.79 | ADORA2B (0.69) | KMT2ARXFP1CYP2C19MAPK1ADORA2A | |
| SCHEMBL2704481 | 0.78 | KMT2A (0.59) | TSHRKMT2ARXFP1CYP2C19MAPK1 | |
| SCHEMBL17475359 | 0.76 | KMT2A (0.58) | TSHRKMT2ARXFP1CYP2C19MAPK1 | |
| SCHEMBL9067375 | 0.76 | KMT2A (0.58) | TSHRKMT2ARXFP1CYP2C19MAPK1 | |
| SCHEMBL10407513 | 0.76 | KMT2A (0.58) | TSHRKMT2ARXFP1CYP2C19MAPK1 | |
| SCHEMBL10668187 | 0.76 | KMT2A (0.58) | TSHRKMT2ARXFP1CYP2C19MAPK1 | |
| SCHEMBL2496142 | 0.76 | CYP2C19 (0.61) | KMT2ARXFP1CYP2C19MAPK1ADORA2A | |
| SCHEMBL9123418 | 0.76 | CYP2C19 (0.59) | TSHRKMT2ARXFP1CYP2C19MAPK1 | |
| SCHEMBL22398941 | 0.76 | KMT2A (0.58) | KMT2ARXFP1CYP2C19MAPK1ADORA2A | |
| SCHEMBL569368 | 0.76 | KMT2A (0.58) | KMT2ARXFP1CYP2C19MAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116650439-A | Preparation method of Ankahuangmin capsules | 广东稳健药业有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-104568534-B | The assay method of Pu'er cooked tea green tea and flavouring essence quality | 云南天士力帝泊洱生物茶集团有限公司 | 2018-08-28 | — | — | CN | claimed |
| CN-104568534-A | Determination method for taste quality and aroma quality of Pu-Er ripe tea | YUNNAN TASLY DEEPURE BIOLOG TEA GROUP CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-117257744-A | Ammoniacus Huang Minxiao pill, ammonia caffeine yellow sensitive capsule and preparation method thereof | 广州白云山光华制药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117257744-A | Ammoniacus Huang Minxiao pill, ammonia caffeine yellow sensitive capsule and preparation method thereof | 广州白云山光华制药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116650439-A | Preparation method of Ankahuangmin capsules | 广东稳健药业有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-104568534-B | The assay method of Pu'er cooked tea green tea and flavouring essence quality | 云南天士力帝泊洱生物茶集团有限公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-108159349-A | A kind of Chinese medicine preparation for treating migraine and preparation method thereof | 王芬 | 2018-06-15 | — | — | CN | disclosed |
| CN-106974025-A | A kind of green fall fire class drink and preparation method | 安徽省天山茶业有限公司 | 2017-07-25 | — | — | CN | disclosed |
| CN-104568534-A | Determination method for taste quality and aroma quality of Pu-Er ripe tea | YUNNAN TASLY DEEPURE BIOLOG TEA GROUP CO LTD | 2015-04-29 | — | — | CN | disclosed |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
| US-7109329-B2 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC | 2006-09-19 | — | — | US | disclosed |
| US-20040092536-A1 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC (US) | 2004-05-13 | — | — | US | disclosed |
| US-6413962-B1 | ANESTHESIA AND TEMPERATURES REDUCTION; ALPHA-ADRENOCEPTOR AGONIST; RESTORATIVE TO CENTRAL NERVOUS SYSTEM, ESPECIALLY MOTOR AND SENSORY FUNCTIONAL LOSSES FROM TRAMATIC SPINAL CORD INJURIES; ANTISPASTICS; NONSEDATIVE; SIDE EFFECT REDUCTION | NAFTCHI N ERIC (US) | 2002-07-02 | — | — | US | disclosed |
| US-5958933-A | HAVING A GUANIDINO GROUP ALIPHATICALLY LINKED TO A XANTHINE GROUP, ADRENERGIC STIMULANTS | NAFTCHI N ERIC (US) | 1999-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092536-A1 | Neurologically active compounds and compounds with multiple activities | ACHE, GRIN2A, GRIK2 | TSHR 4454/4885KMT2A 1274/4885RXFP1 4617/4885 |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | TSHR 813/4885KMT2A 4167/4885RXFP1 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.