Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627810 | 0.86 | FAAH (0.79) | FAAHALDH1A1L3MBTL1RAB9APOLB | |
| SCHEMBL5448245 | 0.84 | FAAH (0.58) | FAAHALDH1A1L3MBTL1RAB9APOLB | |
| SCHEMBL5453555 | 0.82 | FAAH (0.66) | FAAHRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5450845 | 0.80 | FAAH (0.58) | FAAHRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2175738 | 0.80 | FAAH (0.52) | FAAHL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL18279997 | 0.79 | KDM4E (0.59) | ALDH1A1L3MBTL1 | |
| SCHEMBL5233512 | 0.79 | MAPT (0.51) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL5460480 | 0.78 | FAAH (0.55) | FAAHALDH1A1L3MBTL1RAB9APOLB | |
| SCHEMBL2177424 | 0.78 | SIGMAR1 (0.56) | FAAH | |
| SCHEMBL5749445 | 0.77 | MEN1 (0.57) | FAAHPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021405-A1 | ARYL- AND HETEROARYLPIPERIDINECARBOXYLATE-DERIVATIVES METHODS FOR THEIR PREPARATION AND USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021405-A1 | ARYL- AND HETEROARYLPIPERIDINECARBOXYLATE-DERIVATIVES METHODS FOR THEIR PREPARATION AND USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | FAAH, FAAH2, HRH2 | FAAH 1/4885ALDH1A1 1108/4885L3MBTL1 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.