Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | AIP | O00170 | 1/20 | 0.61 |
| ▸ | SGTA | O43765 | 1/20 | 0.61 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.61 |
| ▸ | STIP1 | P31948 | 1/20 | 0.61 |
| ▸ | PPP5C | P53041 | 1/20 | 0.61 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.61 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.61 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447651 | 0.87 | FLT3 (0.65) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5453185 | 0.87 | FLT3 (0.65) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5451446 | 0.86 | AIP (0.71) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5453282 | 0.86 | AIP (0.71) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL8291584 | 0.85 | REV1 (0.61) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL16596087 | 0.84 | REV1 (0.62) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL3916303 | 0.82 | REV1 (0.79) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5451302 | 0.81 | FLT3 (0.70) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5455042 | 0.81 | FLT3 (0.70) | REV1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL8290603 | 0.80 | ALDH1A1 (0.72) | REV1ALDH1A1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | REV1 1861/4885ALDH1A1 1153/4885KDM4E 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.