Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511191 | 0.83 | CASP3 (0.81) | CASP3NR1H3NR1H2TTRCES1 | |
| SCHEMBL12269703 | 0.83 | CASP3 (0.41) | CASP3NR1H3NR1H2DPP4TTR | |
| SCHEMBL28263 | 0.83 | CASP3 (0.81) | CASP3NR1H3NR1H2TTRCES1 | |
| Water SCHEMBL9398503 | 0.80 | CASP3 (0.77) | CASP3NR1H3NR1H2TTRCES1 | |
| Hydrogen Sulfide SCHEMBL11098631 | 0.80 | CASP3 (0.77) | CASP3TTRCES1APPCYP1A2 | |
| Hydrochloric Acid SCHEMBL7736926 | 0.80 | CASP3 (0.77) | CASP3NR1H3NR1H2TTRCES1 | |
| Iodide SCHEMBL30725965 | 0.80 | CASP3 (0.77) | CASP3NR1H3NR1H2TTRCES1 | |
| Hydrogen Sulfide SCHEMBL11121709 | 0.80 | CASP3 (0.77) | CASP3TTRCES1APPCYP1A2 | |
| SCHEMBL29025703 | 0.80 | CASP3 (0.77) | CASP3NR1H3NR1H2TTRCES1 | |
| SCHEMBL7616755 | 0.76 | CASP3 (0.63) | CASP3NR1H3NR1H2TTRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808012-A | Synthesis of folpet | 扬州市荣晶工业助剂有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-111393353-A | Synthesis method of N-methylthio phthalimide | 仪征市海帆化工有限公司 | 2020-07-10 | — | — | CN | claimed |
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |
| CN-111808012-A | Synthesis of folpet | 扬州市荣晶工业助剂有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111808012-A | Synthesis of folpet | 扬州市荣晶工业助剂有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111393353-A | Synthesis method of N-methylthio phthalimide | 仪征市海帆化工有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-111393353-A | Synthesis method of N-methylthio phthalimide | 仪征市海帆化工有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-111393353-A | Synthesis method of N-methylthio phthalimide | 仪征市海帆化工有限公司 | 2020-07-10 | — | — | CN | disclosed |
| EP-3239137-B1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | DU PONT (US) | 2019-02-13 | — | — | EP | disclosed |
| US-9920030-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| US-9920030-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20070190160-A1 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA | 2007-08-16 | — | — | US | disclosed |
| WO-2005020933-A2 | NANOPARTICLES FOR DRUG-DELIVERY | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-1998046683-A1 | COATING COMPOSITIONS COMPRISING BUSOXINONE | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-10-22 | — | — | WO | disclosed |
| EP-0337815-A1 | 1-dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-10-18 | — | — | EP | disclosed |
| US-4532258-A | Controlling insects, mites, pests | KURARAY CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| US-4390547-A | 2,2-Dimethyl-3-(substituted ethyl)cyclopropane carboxylate pesticidal compositions and methods | KURARAY CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4299839-A | Novel pesticides and pesticidal compositions cyclopropanecarboxylates and pesticidal method | KURARAY CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190160-A1 | Nanoparticles for drug-delivery | EPCAM, TUBB1, ACTB | CASP3 593/4885NR1H3 2397/4885NR1H2 3026/4885 |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | ARG1, NAT1, CHRM1 | CASP3 367/4885NR1H3 2352/4885NR1H2 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.