Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455082 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNANPSR1EPHX1 | |
| SCHEMBL12067341 | 0.86 | SIRT1 (0.71) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 | |
| SCHEMBL28662121 | 0.83 | SIRT1 (0.68) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 | |
| SCHEMBL5453192 | 0.82 | EPHX1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 | |
| SCHEMBL5454023 | 0.82 | EPHX1 (0.49) | ALDH1A1SMN1; SMN2NPSR1EPHX1KDM4E | |
| SCHEMBL5464193 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNASMN1; SMN2SIRT2 | |
| SCHEMBL2344788 | 0.81 | KMT2A (0.68) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 | |
| SCHEMBL907582 | 0.81 | SIRT1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 | |
| SCHEMBL12940302 | 0.81 | SIRT1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 | |
| SCHEMBL16677195 | 0.81 | SIRT1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |