Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455082 | 0.78 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1ALOX12KMT2A | |
| SCHEMBL5464193 | 0.75 | ALDH1A1 (0.59) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5453192 | 0.73 | EPHX1 (0.65) | MAPTALDH1A1MEN1ALOX12KMT2A | |
| SCHEMBL5454023 | 0.73 | EPHX1 (0.49) | ALDH1A1MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL5459767 | 0.73 | ALDH1A1 (0.59) | MAPTALDH1A1NPSR1KDM4EEPHX1 | |
| SCHEMBL13956786 | 0.69 | EPHX1 (0.62) | MAPTALDH1A1MEN1ALOX12KMT2A | |
| SCHEMBL861663 | 0.68 | MAPT (0.50) | MAPTALDH1A1MEN1ALOX12KMT2A | |
| SCHEMBL5452764 | 0.68 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5451532 | 0.67 | PLK1 (0.47) | KMT2AKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL4185021 | 0.67 | ALDH1A1 (0.60) | MAPTALDH1A1MEN1ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |