Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.85 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.85 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.73 |
| ▸ | DUSP22 | Q9NRW4 | 4/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.63 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.61 |
| ▸ | CFTR | P13569 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | NSD2 | O96028 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455212 | 1.00 | HSPD1 (0.85) | HSPD1HSPE1DUSP26DUSP22DUSP3 | |
| SCHEMBL2403963 | 0.90 | HSPD1 (0.81) | HSPD1HSPE1DUSP26DUSP22DUSP3 | |
| SCHEMBL2403960 | 0.90 | HSPD1 (0.81) | HSPD1HSPE1DUSP26DUSP22DUSP3 | |
| SCHEMBL2403957 | 0.90 | HSPD1 (0.81) | HSPD1HSPE1DUSP26DUSP22DUSP3 | |
| SCHEMBL14788063 | 0.89 | HSPD1 (0.76) | HSPD1HSPE1DUSP26DUSP22DUSP3 | |
| SCHEMBL5461744 | 0.87 | HSPD1 (0.70) | HSPD1HSPE1DUSP26DUSP22HSD17B3 | |
| SCHEMBL5461746 | 0.87 | HSPD1 (0.70) | HSPD1HSPE1DUSP26DUSP22HSD17B3 | |
| SCHEMBL12671881 | 0.87 | CFTR (0.79) | HSPD1HSPE1DUSP26DUSP22HSD17B3 | |
| SCHEMBL2489942 | 0.87 | DUSP26 (0.73) | HSPD1HSPE1DUSP26DUSP22CFTR | |
| SCHEMBL14788077 | 0.87 | DUSP26 (0.73) | HSPD1HSPE1DUSP26DUSP22CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | HSPD1 2213/4885HSPE1 1812/4885DUSP26 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.