Indigotindisulfonate

Indigotindisulfonate

SCHEMBL5455215

O=C1/C(=C2/Nc3ccc(S(=O)(=O)O)cc3C2=O)Nc2ccc(S(=O)(=O)O)cc21

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
CASP3 P42574 8/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
CASP9 P55211 1/20 0.47
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TGM2 P21980 3/20 0.38
CES1 P23141 3/20 0.38
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CAPN9 O14815 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indigotindisulfonate SCHEMBL2727226 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL2732840 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL29387846 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL186297 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL3652418 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL3680504 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL29694234 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL186296 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL9107944 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL3960977 0.96 CA12 (0.47) CA12CA1CA2CA9CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839591-B2 Anionic dye or brightener bearing an ammonium or phosphonium counterion, dye composition comprising them and process for dyeing keratin fibres using these dyes L'OREAL (FR) 2017-12-12 US disclosed
US-9839591-B2 Anionic dye or brightener bearing an ammonium or phosphonium counterion, dye composition comprising them and process for dyeing keratin fibres using these dyes L'OREAL (FR) 2017-12-12 US disclosed
US-20170229738-A1 ELECTROLYTE FOR NONAQUEOUS SECONDARY BATTERY AND NONAQUEOUS SECONDARY BATTERY USING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-08-10 US disclosed
US-20170187060-A1 INEXPENSIVE METAL-FREE ORGANIC REDOX FLOW BATTERY (ORBAT) FOR GRID-SCALE STORAGE U.S. DEPARTMENT OF ENERGY 2017-06-29 US disclosed
EP-3182501-A1 ELECTROLYTE FOR NONAQUEOUS SECONDARY CELL AND NONAQUEOUS SECONDARY CELL USING SAME National Institute of Advanced Industrial Science and Technology (JP) 2017-06-21 EP disclosed
WO-2017093866-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF INDIGO CARMINE DISHMAN PHARMACEUTICALS AND CHEMICALS LIMITED (IN) 2017-06-08 WO disclosed
US-9670524-B2 Test elements for determining an analyte concentration that include correction information for at least one interfering variable ROCHE DIABETES CARE, INC. (US) 2017-06-06 US disclosed
US-9614245-B2 Inexpensive metal-free organic redox flow battery (ORBAT) for grid-scale storage UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2017-04-04 US disclosed
US-20170073499-A1 LATEX COMPRISING COLORANT AND METHODS OF MAKING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2017-03-16 US disclosed
US-9580578-B2 Latex comprising colorant and methods of making the same XEROX CORPORATION (US) 2017-02-28 US disclosed
WO-2007130982-A2 AQUEOUS ANTISEPTIC SOLUTION AND COMPATIBLE ANIONIC DYE FOR STAINING SKIN ENTURIA, INC. (US) 2007-11-15 WO disclosed
US-20070253909-A1 Aqueous Antiseptic Solution and Compatible Cationic Dye for Staining Skin MEDI-FLEX, INC. (US) 2007-11-01 US disclosed
US-20070254854-A1 Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin MEDI-FLEX, INC. (US) 2007-11-01 US disclosed
US-20070249012-A1 Microbial Detection and Quantification KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-10-25 US disclosed
US-20070186808-A1 CYAN INK FOR INK-JET RECORDING BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-08-16 US disclosed
US-20070092579-A1 Medical Products and Parenteral Formulations BAXTER HEALTHCARE S.A. (CH) 2007-04-26 US disclosed
US-20070048608-A1 Redox-active polymers and their applications BROWN UNIVERSITY 2007-03-01 US disclosed
US-20070031976-A1 Oxygen Indicator for Use in Medical Products BAXTER INTERNATIONAL INC. 2007-02-08 US disclosed
US-20070029001-A1 Multiple Chamber Container BAXTER HEALTHCARE S.A. (CH) 2007-02-08 US disclosed
US-20070010573-A1 Methods and compositions for treating amyloid-related diseases BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070253909-A1 Aqueous Antiseptic Solution and Compatible Cationic Dye for Staining Skin CUTA, POLR1C, TYR CA12 122/4885CA1 637/4885CA2 190/4885
US-20070092579-A1 Medical Products and Parenteral Formulations PROC, SLC5A6, PNLIP CA12 1021/4885CA1 2191/4885CA2 875/4885
US-20070254854-A1 Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin CUTA, IK, POLR1C CA12 89/4885CA1 907/4885CA2 199/4885
US-20070010573-A1 Methods and compositions for treating amyloid-related diseases APP, PSEN1, PSEN2 CA12 998/4885CA1 582/4885CA2 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.