Indigotindisulfonate

Indigotindisulfonate

SCHEMBL2732840

O=C1/C(=C2\Nc3ccc(S(=O)(=O)O)cc3C2=O)Nc2ccc(S(=O)(=O)O)cc21

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
CASP3 P42574 8/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
CASP9 P55211 1/20 0.47
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TGM2 P21980 3/20 0.38
CES1 P23141 3/20 0.38
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CAPN9 O14815 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indigotindisulfonate SCHEMBL2727226 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL29387846 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL5455215 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL186297 1.00 CA12 (0.50) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL3652418 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL3680504 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL29694234 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL186296 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL9107944 0.98 CA12 (0.49) CA12CA1CA2CA9CASP3
Indigotindisulfonate SCHEMBL3960977 0.96 CA12 (0.47) CA12CA1CA2CA9CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398826-A1 PHARMACEUTICAL FORMULATION HOFFMANN-LA ROCHE INC. (US) 2024-12-05 US claimed
US-12083127-B2 Pharmaceutical formulation HOFFMANN-LA ROCHE INC. (US) 2024-09-10 US claimed
US-20230390302-A1 PHARMACEUTICAL FORMULATION HOFFMANN-LA ROCHE INC. (US) 2023-12-07 US claimed
US-20230054407-A1 OPTICAL BIOPSY STAIN PANELS AND METHODS OF USE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-02-23 US claimed
EP-4082535-A1 PHARMACEUTICAL FORMULATION F. Hoffmann-La Roche AG (CH) 2022-11-02 EP claimed
EP-3720424-B1 PHARMACEUTICAL FORMULATION HOFFMANN LA ROCHE (CH) 2022-09-21 EP claimed
EP-3720424-A1 PHARMACEUTICAL FORMULATION H. Hoffnabb-La Roche Ag (CH) 2020-10-14 EP claimed
US-20200297732-A1 PHARMACEUTICAL FORMULATION HOFFMANN-LA ROCHE INC. (US) 2020-09-24 US claimed
WO-2019110723-A1 PHARMACEUTICAL FORMULATION F. HOFFMANN-LA ROCHE AG (CH) 2019-06-13 WO claimed
EP-4712785-A1 CHEWABLE COMPOSITIONS COMPRISING PECTIN AND UROLITHIN Amazentis SA (CH) 2026-03-25 EP disclosed
US-12576064-B2 Urolithin gummy (pectin) formulations AMAZENTIS SA (CH) 2026-03-17 US disclosed
US-20250381253-A1 MUTANASES AND ORAL CARE COMPOSITIONS COMPRISING SAME NOVOZYMES A/S (DK) 2025-12-18 US disclosed
US-20250375412-A1 UROLITHIN GUMMY (PECTIN) FORMULATIONS AMAZENTIS SA (CH) 2025-12-11 US disclosed
US-20250367159-A1 UROLITHIN GUMMY (PECTIN) FORMULATIONS AMAZENTIS SA (CH) 2025-12-04 US disclosed
EP-0132472-A1 Medicated products containing a magnesium trisilicate adsorbent with a medicament drug adsorbed thereon WARNER-LAMBERT COMPANY (US) 1985-02-13 EP disclosed
US-4499001-A DENTURE CLEANER WARNER-LAMBERT COMPANY (US) 1985-02-12 US disclosed
US-4409118-A Tablet forming cleanser composition and method of preparation WARNER-LAMBERT COMPANY (US) 1983-10-11 US disclosed
US-4388328-A WITH MANNITOL AND SACCHARIN WARNER-LAMBERT COMPANY (US) 1983-06-14 US disclosed
US-4362639-A OXIDIZERS, BLEACHES WARNER-LAMBERT COMPANY (US) 1982-12-07 US disclosed
US-4012250-A Imaging system XEROX CORPORATION (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576064-B2 Urolithin gummy (pectin) formulations PYGM, HAGH, GYS1 CA12 3554/4885CA1 4404/4885CA2 3811/4885
US-20230390302-A1 PHARMACEUTICAL FORMULATION CYP4B1, GABRA5, CYP2C8 CA12 3789/4885CA1 3791/4885CA2 1748/4885
US-20250375412-A1 UROLITHIN GUMMY (PECTIN) FORMULATIONS PYGM, GALE, GYS1 CA12 1553/4885CA1 3141/4885CA2 1890/4885
US-20250367159-A1 UROLITHIN GUMMY (PECTIN) FORMULATIONS PYGM, GALE, GYS1 CA12 1553/4885CA1 3141/4885CA2 1890/4885
US-20240398826-A1 PHARMACEUTICAL FORMULATION GRIK5, GABRA5, HTR5A CA12 4334/4885CA1 3797/4885CA2 3385/4885
US-12083127-B2 Pharmaceutical formulation HTR1A, HTR5A, HTR1D CA12 3979/4885CA1 2537/4885CA2 4185/4885
US-20200297732-A1 PHARMACEUTICAL FORMULATION CYP4B1, GABRA5, CYP2C8 CA12 3789/4885CA1 3791/4885CA2 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.